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Craniofacial defects such as cleft lip and cleft palate are among the most common of all birth defects. Currently there are no national data for cleft lip or palate. The National Birth Defects Prevention Network (NBDPN) collects cleft lip and palate data annually from 11 states (Alabama, Arkansas, California, Georgia, Hawaii, Iowa, Massachusetts, North Carolina, Oklahoma, Texas, and Utah), which provides a means for estimating national data.
The Common Fund’s Gabriella Miller Kids First Pediatric Research Program (Kids First) is developing a large-scale data resource to help researchers uncover new insights into the biology of childhood cancer and structural birth defects, including the discovery of shared genetic pathways between these disorders.
The goal of the Illuminating the Druggable Genome (IDG) program is to improve our understanding of the properties and functions of proteins that are currently unannotated within the three most commonly drug-targeted protein families: G-protein coupled receptors, ion channels, and protein kinases.
The Center for Craniofacial and Dental Genetics (CCDG) is a collaborator in several large-scale, National Institutes of Health (NIH)-sponsored genomic studies including the Gene Environment Association Studies Initiative (GENEVA) and genome-wide association study (GWAS) initiatives to better understand the genetics of dental caries and oral clefts. Genotype and phenotype datasets from these studies are available to investigators around the world through the NIH’s dbGaP (Database of Genotypes and Phenotypes : https://www.ncbi.nlm.nih.gov/gap
The FDI Data Hub is a one-stop shop for global oral health data. Data sources are from publicly available from international sources including the World Health Organization (GHO and Infobase), Niigata University, Malmö University, World Bank and Globocan. Includes data visualization tools, maps and tables.
ADDEP provides access to data including a wide range of topics related to disability. ADDEP data can be used to better understand and inform the implementation of the Americans with Disabilities Act and other disability policies.
BioGRID is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications from major model organism species. All interaction data are freely provided through our search index and available via download in a wide variety of standardized formats.
The PhysioNet Resource is intended to stimulate current research and new investigations in the study of complex biomedical and physiologic signals. It offers free web access to large collections of recorded physiologic signals (PhysioBank) and related open-source software (PhysioToolkit).
dbSNP is a general public archive of all short sequence variation, not just single nucleotide substitutions that occur frequently enough in a population to be termed polymorphic, but also rare variants, including those with clinical assertions in ClinVar.
tate Cancer Profiles characterizes the cancer burden in a standardized manner to motivate action, integrate surveillance into cancer control planning, characterize areas and demographic groups, and expose health disparities
The NIDA Data Share web site is an electronic environment that allows data from completed clinical trials to be distributed to investigators and the public in order to promote new research, encourage further analyses, and disseminate information to the community.
The National Health and Nutrition Examination Survey (NHANES) is a program of studies designed to assess the health and nutritional status of adults and children in the United States. The survey is unique in that it combines interviews and physical examinations.
The Oral Health Data website contains data for indicators from the National Oral Health Surveillance System (NOHSS), Water Fluoridation Statistics biennial reports, and the annual Synopses of State Oral Health Programs. State-level data are provided for all indicators. National-level data of state-level data are also provided. Synopses data provided by ASTDD include additional context for the NOHSS indicators. Data are added as new data become available.
MEPS collects information on the nature of any dental care visit/use/event, type of dental care provider, treatments and services performed, and prescribed medicines. Dental expenditures include all direct payments by individuals, private insurance (including TRICARE), Medicare, Medicaid, and other sources such as the Veterans Administration, Workers' Compensation, and miscellaneous public sources to providers of the services.
500 Cities Project is to provide city- and census tract-level small area estimates for chronic disease risk factors, health outcomes, and clinical preventive service use for the largest 500 cities in the United States.
CDC: Behavioral Risk Factor Surveillance System (BRFSS)
state data about U.S. residents regarding their health-related risk behaviors, chronic health conditions, and use of preventive services
Program aims to create a network-based understanding of biology by cataloging changes in gene expression and other cellular processes that occur when cells are exposed to a variety of perturbing agents.
The Genotype-Tissue Expression (GTEx) project aims to provide to the scientific community a resource with which to study human gene expression and regulation and its relationship to genetic variation. This project will collect and analyze multiple human tissues from donors who are also densely genotyped, to assess genetic variation within their genomes
Curated gene expression data sets, as well as original Series and Platform records in the Gene Expression Omnibus (GEO) repository. Enter search terms to locate experiments of interest. DataSet records contain additional resources including cluster tools and differential expression queries